Although our human body can produce natural hyaluronic acid by itself, as we age, the speed of our body’s production rate cannot keep up with the pace of loss.Â
Natural Hyaluronic Acid is very easy to break down. By converting the liquid into a gel, the polymer chains are cross-linked to maintain shape for a longer period of time and slow the disintegration process.
Currently, dermal fillers are synthesized by pharmaceutical laboratories and made by natural enzyme polymerization. However, due to the difference in raw materials and process technology, the characteristics and effects of hyaluronic acid filler are also different.
Let’s take a look at what are the top 5 hyaluronic acid brands.
No. 5 Neuramis dermal filler

Neuramis filler is manufactured using a high-quality hyaluronic acid that is registered in the Drug Master Files (DMFs) of FDA and certified by the European Directorate for the Quality of Medicines (EDQM).
Neuramis raw materials comply with even higher standards than required by the European Pharmacopoeia (Ph. Eur) to enhance safety.
Neuramis fillers are divided into 3 types: Neuramis Lidocaine, Neuramis Deep Lidocaine and Neuramis Volume Lidocaine.
- Neuramis lidocaine is mostly used to treat fine lines such as crow’s feet, lip lines, etc.
- Neuramis deep lidocaine is mainly for lips enhancement, nasolabial folds removal, under eyes correction, etc.
- Neuramis volume lidocaine contains the biggest HA particle, it is mostly used for nose shaping, facial contour, jawline, chin augmentation, cheeks filling, etc.
Because of lidocaine is added to the filler, you don’t have to worry about pain.
No. 4 Hyaldew dermal filler

HyalDew Hyaluronic Acid Dermal Fillers overcome the limitations of traditional hyaluronic acid cross-linking technology by developing its patented microbeads using HyalDew’s exclusive multi-stage cross-linking technology. These occur in three distinct stages to provide more stable molecular structures and higher cross-linking rates. This in turn solves the short duration of traditional HA dermal fillers.
Hyaldew applies the patented technology of microbead processing in 3 stages that allow it to increase the viscosity and produce a long-lasting filling.
No. 3 Oyemi filler

Oyemi is a new brand from Korea, but its effects got very good feedback from customers.
It adopts eight special procedures to remove impurities, and also uses multiple filter membranes to not only remove impurities but also remove residual BDDE.Â
Oyemi has three models: Fine, Deep, and Volume. Fine is used for fine lines, deep for lips, nasolabial folds, tear trough, etc, volume is for chin and cheeks augmentation, nose shaping, temple filling, etc.
No. 2 Restylane filler

Restylane hyaluronic acid injection is a high-tech product from Sweden. It is a non-toxic, non-rejecting, non-allergic and inflammatory dermal filler product. It has excellent compatibility with the human body. It is stable and the effects are very natural after injection.
No. 1 Juvederm

Juvederm dermal filler is the No 1 filler brand. Produced by Allergan, one of the top 500 companies in the world. It has been certified by many international drug administrations such as European CE and American FDA. It has been marketed and used in more than 100 countries around the world, and the global sales volume has exceeded 27 million boxes.Â