Hyaluronic Acid Knowledge

Profhilo Injection: A Non-Surgical Fountain of Youth

profhilo filler

What is Profhilo Injection?

Profhilo injection is a cutting-edge, injectable treatment that utilizes hyaluronic acid, a naturally occurring substance in our skin, to improve skin quality, hydration, and texture. It’s often called “skin remodeling” because it doesn’t just address specific concerns but revitalizes the entire face.

profhilo injection

Profhilo Injection Parameters

NameProfhilo injection
TypeInjectable treatment
Active IngredientHyaluronic Acid (HA)
Production TechniqueBio-fermentation using patented NAHYCO® technology
Concentration of HA64 mg per 2 mL (32 mg/mL)
IndicationsSkin hydration, fine lines, wrinkles, skin laxity, skin rejuvenation
DurationResults typically last up to 6 months
Treatment TechniqueBi-phasic injection technique into specific points on the face, usually in five key areas
Pain LevelMinimal discomfort; well-tolerated
DowntimeMinimal; patients can usually resume normal activities immediately
ResultsImproved skin hydration, enhanced firmness, reduction in fine lines and wrinkles, natural look
Number of SessionsTwo sessions, spaced approximately one month apart, are typically recommended
MaintenanceFollow-up sessions every 6-12 months may be advised to maintain results
Side EffectsMild redness, swelling, or tenderness at injection sites, typically temporary and short-lived
ManufacturerIBSA Farmaceutici Italia Srl
FDA ApprovalProfhilo is CE-marked, meaning it has European approval for use; approval status may vary by region

What is the difference between profhilo injection and other dermal fillers?

Prophilo injection and traditional dermal fillers are both used in the field of aesthetic medicine, but they have some key differences in terms of their composition, purpose, and application:


Prophilo is a hyaluronic acid-based product, like traditional dermal fillers. However, its hyaluronic acid is specially formulated to have a low concentration and a unique structure, which makes it ideal for skin bioremodeling and hydration. It is not intended to add volume to specific areas but rather to improve overall skin quality.

Traditional dermal fillers are typically formulated with hyaluronic acid, collagen, or other materials, depending on the brand and type. Their primary purpose is to add volume to specific areas of the face or body, such as lips, cheeks, and wrinkles.


Prophilo injection is mainly used for skin bioremodeling and hydration. It stimulates the production of collagen and elastin, leading to improved skin texture, elasticity, and hydration. It is designed to provide a more natural and subtle enhancement of the skin’s overall quality.

Traditional dermal fillers are used to address various concerns, including adding volume to specific areas, smoothing out wrinkles and fine lines, enhancing facial contours, and plumping lips. They are more focused on creating immediate and localized improvements.


Prophilo injection is administered using a specific injection technique, which involves five injection points on each side of the face. The treatment typically requires two sessions spaced about four weeks apart. It is injected just beneath the skin’s surface, resulting in minimal discomfort and little to no downtime.

Traditional dermal fillers can be injected at different depths, depending on the specific treatment area and the desired results. The injection technique may vary, and the practitioner will typically aim to provide immediate volume enhancement or wrinkle reduction.

Duration of Results:

The results of Prophilo injection are typically longer-lasting compared to traditional dermal fillers for skin quality improvement. Patients may enjoy improvements in skin quality for up to six months or more.

The duration of results with traditional dermal fillers can vary depending on the type of filler used and the area treated, but they usually last from several months to a year or more.

In summary, Prophilo is focused on skin bioremodeling, hydration, and overall skin quality improvement, while traditional dermal fillers are designed to add volume and address specific cosmetic concerns.

What exactly does Profhilo do?

Prophilo injection is a unique hyaluronic acid-based treatment designed for skin bioremodeling and hydration. It can:

Stimulates Collagen and Elastin Production: Prophilo contains a specially formulated hyaluronic acid with a low concentration. When injected beneath the skin, it triggers the body’s natural production of collagen and elastin. These proteins are essential for maintaining the skin’s elasticity, firmness, and overall quality.

Enhances Skin Hydration: Hyaluronic acid is a natural substance that is known for its ability to attract and retain moisture. Prophilo acts as a hydrating agent, promoting improved skin hydration. This leads to a more radiant and youthful appearance, as well as a smoother texture.

Bioremodeling: Unlike traditional dermal fillers, which are primarily used to add volume to specific areas, Prophilo injection is focused on improving the overall quality of the skin. It doesn’t aim to create dramatic changes in facial features but instead works to enhance the skin’s natural beauty and health.

Even Distribution: Prophilo is administered through a specific injection technique that involves injecting the product at five key points on each side of the face. This technique ensures even distribution, promoting overall skin improvement and a harmonious look.

Subtle and Natural-Looking Results: Prophilo delivers subtle and natural results. It doesn’t create a “plumped” or “overfilled” appearance, making it suitable for individuals looking to achieve a refreshed and rejuvenated look without drastic changes.

Long-Lasting Results: Many patients experience improvements in skin quality that can last for up to six months or more. The longevity of Prophilo’s effects is one of its key advantages.

Versatility: Prophilo injection can be used on various areas of the body, such as the face, neck, décolletage, and hands, to address skin aging and hydration concerns.

Little to No Downtime: Prophilo treatments typically involve minimal discomfort, with some patients experiencing mild redness or swelling that usually resolves within a day or two. This means that there is little to no downtime associated with the procedure.

Which is better Botox or Profhilo injection?

Botox and Prophilo are different treatments with distinct purposes, and their effectiveness varies depending on what you’re looking to achieve:

PurposeTemporarily reduces dynamic wrinklesSkin bioremodeling and hydration
Mechanism of ActionRelaxes musclesStimulates collagen and elastin production
ResultsQuick results (days to weeks)Gradual and subtle (weeks to months)
Duration of Results3-6 monthsUp to 6 months or more
Treatment AreasUpper face (expression lines)Face, neck, décolletage, hands, and more
Natural-LookingNatural-looking when administered skillfullySubtle and natural, maintains facial expressiveness
DowntimeMinimal to noneMinimal discomfort, potential for mild redness

Leave a Reply

Your email address will not be published. Required fields are marked *